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The OUMERE March Edition Arrives March 1st, 2026. Quantities Limited

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Serum Bioluminelle™

200.00
Volume
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Serum Bioluminelle™

200.00

Step IV of the OUMERE Protocol

The final step. Where the system is sealed.

Acquire The Collection Start with the Travel Set
Step IV — The Lipid Seal

Serum Bioluminelle

Everything applied in Steps I through III — the renewal, the antioxidants, the peptides — needs to be held in place. Serum Bioluminelle is the seal. A dual-phase hydro-lipid finishing serum that locks in the work of the entire protocol while leaving the skin luminous, comfortable, and breathable.

Not a cream. Not a moisturizer. A balanced lipid architecture — watermelon seed oil, grapeseed, black seed, black currant, prickly pear — in a formula that wears like nothing at all. Hand-compounded in limited monthly editions.

OUMERE Serum Bioluminelle — hand-compounded dual-phase hydro-lipid finishing serum for anti-aging skin protection

Why Creams Were Left Behind

Beyond Occlusion

Traditional creams rely on waxes and heavy occlusives that sit on top of the skin, trapping heat and creating the feel of moisture without actually supporting the skin's own comfort long-term. Bioluminelle takes a different approach — a lightweight lipid profile that helps skin look and feel hydrated without the heaviness or congestion.

The Dual Phase

Skin's surface is naturally a balance of water and oil. Bioluminelle reflects that duality. Shake the bottle to combine the aqueous and lipid layers, then apply — the result is a finish that looks polished and luminous, feels weightless, and allows the skin to remain comfortable and breathable throughout the day.

The Finishing Layer

As the final step in the OUMERE Protocol, Bioluminelle helps retain the benefits of the layers applied before it. Its high-linoleic lipid profile — rich in grapeseed, watermelon seed, and black currant oils — helps the skin appear calm, even-toned, and luminous. The morning architecture, complete.

Formulation Principles

What a finishing serum should be — and what it should never contain.

No Fragrance

The final layer applied to the skin should be the purest. Bioluminelle contains no fragrance — synthetic or from essential oils — ensuring the finishing seal is calming, not irritating, on skin that has already received three active treatment steps.

No Hyaluronic Acid

Topical HA draws moisture to the skin's surface where it can be lost to evaporation. Bioluminelle's hydration comes from its botanical lipid complex and beta-glucan — supporting a hydrated, comfortable feel that lasts throughout the day.

No Creams or Waxes

Bioluminelle was developed as a departure from traditional moisturizers. No waxes, no heavy occlusives, no thickening agents. The formula is a true dual-phase serum — oil and water in balance — that leaves skin looking luminous and feeling weightless rather than coated.

Hand-Compounded

The cold-pressed oils and botanical extracts in Bioluminelle are sensitive to heat and prolonged storage. Each monthly edition is compounded individually in the OUMERE private laboratory — preserving the freshness and integrity of every oil in the formula.

The Ritual

Shake the bottle side to side to combine the oil and water layers. Dispense a dime-sized amount and press into the skin. Apply in the morning after The Advancement, and in the evening as the final step of the PM protocol. Allow 60 seconds before applying sunscreen.

For dry skin, use a slightly larger amount. For oily or acne-prone skin, start with less and increase as the skin acclimates. Bioluminelle is the finish — the layer that determines how your skin looks and feels for the rest of the day. It should feel like silk, not like product.

Full INCI: Aloe Barbadensis Leaf Juice, Carrot Seed Oil, Watermelon Seed Oil, Glycerin, Goldenseal Extract, Macrocystis pyrifera Extract, Broccoli Sprout Extract, Camellia japonica Seed Oil, Black Seed Oil, Prickly Pear Seed Oil, Ginseng Extract, Green Coffee Oil, Avocado Oil, Grapeseed Oil, Beta-Glucan, Cilantro Extract, Horse Chestnut Extract, Black Currant Oil, Guava Oil, Wasabi Extract, Mannentake Extract, Reishi Extract, Shiitake Extract, Ursolic Acid.

About Serum Bioluminelle

OUMERE Serum Bioluminelle is a hand-compounded dual-phase hydro-lipid finishing serum created by cellular biologist Wendy Ouriel in the OUMERE private laboratory in Palm Beach, Florida. It is Step IV of the OUMERE Protocol — the final layer that completes the morning and evening anti-aging skincare system.

The formula features a high-linoleic lipid profile built from cold-pressed watermelon seed oil, grapeseed oil, black seed oil, black currant oil, prickly pear seed oil, camellia japonica seed oil, avocado oil, and guava oil — alongside botanical extracts including goldenseal, broccoli sprout, ginseng, reishi, shiitake, and wasabi. Beta-glucan provides additional comfort and hydration support.

Serum Bioluminelle was developed as a replacement for traditional creams and moisturizers — a lightweight, breathable lipid seal that helps the skin look luminous, calm, and hydrated without the heaviness, congestion, or wax-based occlusion of conventional formulas. It is used in both AM and PM protocols.

Produced in limited monthly volume, bottled in laboratory glass, shipped directly from the OUMERE laboratory. No fragrance. No essential oils. No drying alcohols. No hyaluronic acid. No waxes or heavy occlusives.

For most, OUMERE is the last skincare they will ever need. For many, it is the first that actually worked.

"A serum that wears like couture — tailored, weightless, and made for your skin alone."

Morning Architecture Complete

OUMERE products are formulated for cosmetic use, focusing on the visible health and aesthetic quality of the skin. They are not intended to diagnose, treat, or cure any medical condition.

Apply Serum Bioluminelle after UV-R.
Shake container well to thoroughly mix the water and oil phase layers.
Dispense a pea-sized amount onto fingertips and gently massage onto your face, neck, and décolleté.
Allow product to seep into skin for at least one minute before applying additional products. Serum Bioluminelle™ can be applied up to two times per day for maximum results and benefits.

CARROT SEED OIL

High in beta carotene to keep skin's appearance youthful

URSOLIC ACID

When topically applied, ursolic acid keeps skin's appearance looking youthful

BETA GLUCAN

Naturally improves the appearance of aged skin

WATERMELON SEED OIL, BLACK SEED OIL, and BLACK CURRANT SEED OIL

High in anti-inflammatory fatty acids, which improve the appearance of acne-prone, oily and imbalanced skin

SEA KELP EXTRACT

Rich in silicon, vitamins and minerals to rejuvenate skin

SHIITAKE & REISHI MUSHROOM EXTRACTS

Promotes the appearance of rejuvenated skin

GOLDENSEAL (INDIAN TURMERIC) EXTRACT

For the natural improvement of the appearance of skin redness and acne

BROCCOLI SPROUT EXTRACT

Exclusive OUMERE blend. Topically applied broccoli sprout extract improves appearance of UV damaged skin.

PRICKLY PEAR SEED OIL

Rich oil that preserves skin's youthful appearance

GREEN COFFEE OIL

Naturally improves skin's appearance and prevents skin dryness by locking in moisture

GINSENG EXTRACT

Powerful antioxidant which improves skins appearance with each use

GRAPE SEED OIL

High in high in anti-inflammatory fatty acids to balance skin's appearance and lock in moisture

CILANTRO EXTRACT

Exerts antioxidant activity to keep skins appearance young

WASABI EXTRACT

Improves appearance of age-related degradation of skin and improves appearance of dermatitis

ALOE BARBADENSIS LEAF JUICE

Skin soothing hydration ingredient for skin

INGREDIENTS
Aloe barbadensis leaf juice*, carrot seed oil*, watermelon seed oil*, glycerin*, goldenseal (Indian turmeric) extract*, Macrocystis pyrifera (sea kelp) extract*, broccoli sprout extract*, Camellia japonica seed oil*, black seed oil*, prickly pear seed oil*, ginseng extract*, green coffee oil*, avocado oil*, grapeseed oil*, beta glucan*, cilantro extract*, horse chestnut extract*, black currant oil*, guava oil*, wasabi extract*, mannentake extract*, reishi extract*, shiitake extract*, ursolic acid*, phenyoxyethanol, sorbic acid*, caprylyl glycol*

 *natural

  • Appearance of a natural youthful glow
  • Improvement in appearance of skin's hydration levels
  • Improvement in appearance of aged skin
  • Improvement in appearance of hyperpigmentation

Customer Reviews

Based on 41 reviews
90%
(37)
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N
Nancy Hyman
Sumptuous

Fabulous feel to the product and very little is needed for results. Press into face and neck as a first step before sunscreen during the day. I also use it at night with a slightly more generous application.

A
Angela Deane
Utterly divine.

The smell, the feel, the hydration! One of my very favorite sensorial moments of the day is applying Bioluminelle. I am excited to upgrade the the Concentrate version next.

L
Lindsey Giacomini
So light and moisturizing!

I love this serum! It's so light yet hydrating. No breakouts. Great for mature sensitive skin

M
M Leones
LOVE this product!

This is the second bottle of oil serum I’ve purchased. It is excellent. There is nothing else like it. I have combination skin and this never makes my skin greasy at all! It’s absolutely perfect. I only need to put it on in the evening after my cleanse. Love the purity of the product. I am 58 years old and my skin is glowing like never before! Unmatched!

S
Sabrina Polla
First and last of its kind

This serum is the serum to end all others. I love it beyond words. I go to bed looking like a glazed honey ham and wake up with the most beautiful, soft, filtered skin of my life. I actually love the bottle and packaging. The long-necked vial allows for proper mixing of the water and oil phases and the dropper allows proper application to my forehead cheeks and nose. This serum is truly amazing. Thank you so much Wendy and staff!!