Provenance
Small-cycle composition in Palm Beach. A formula that prioritizes signal transmission over cosmetic feel—no silicones to block peptide absorption.
Advancement Concentrate
550.00
OUMERE • Peptide Renewal Concentrate
The Advancement Concentrate™
Skin types: Normal · Combination · Dry · Sensitive Texture: Lightweight serum Finish: Fragrance-free · Non-occlusive Use: AM core peptide step (optional PM)
A bio-mimetic signal serum informed by longevity research. The Advancement uses a calibrated complex of Matokine-mimetic peptides (Palmitoyl Tripeptide-5 & Dipeptide-5) to target the visible signs of Dermal-Epidermal Junction (DEJ) fatigue. Enhanced with Wasabi and Resveratrol, it promotes the appearance of structural integrity and bounce without the use of occlusive silicones.
| What it is | Cellular signaling serum for structural resilience |
|---|---|
| Size | 60 mL |
| Texture | Water-light, fast-absorbing (Hydrophilic) |
| Scent | No added fragrance (Clinical purity) |
| How to use |
AM: After UV-R, before Serum Bioluminelle. PM (optional): Before evening antioxidant (e.g., UV-R Concentrate) if not using Advancement II. |
Composition
Signal peptides (Palmitoyl Tripeptide-5; Palmitoyl Dipeptide-5 complex) alongside Oxidoreductases, Wasabi, and Resveratrol. A profile designed to mimic the skin's natural regeneration signals.
Ritual
Morning anchor over UV-R and under Bioluminelle. The essential step for maintaining the appearance of firmness and lift.
Biological Mechanism of Action
Palmitoyl Tripeptide-5
A small bioactive peptide that mimics thrombospondin-1 (TSP-1) to activate latent TGF-β, signaling the synthesis of collagen for visible firmness.
Dipeptide-5 Complex
Targets the Dermal-Epidermal Junction (DEJ) by supporting the proteins (Laminin V, Collagen IV) responsible for skin structural cohesion.
Wasabi Extract (Isothiocyanates)
A potent activator of the Nrf2 pathway, stimulating the skin's own antioxidant enzymes to defend against DNA damage and oxidative aging.
Resveratrol
A polyphenol that mimics caloric restriction signaling (Sirtuins) to prolong the appearance of cellular vitality and reduce micro-inflammation.
“Daily peptide discipline. We feed the skin 'signals,' not just moisture.”
What it does (cosmetic)
- Improves the appearance of surface bounce and density.
- Refines texture by supporting the skin's structural scaffolding.
- Strengthens the look of the Dermal-Epidermal Junction (DEJ).
Signature pairings
- No. 9 — calibrated renewal
- UV-R — antioxidant conditioning
- Serum Bioluminelle — finishing moisture
- The Advancement II — denser night counterpart
Sensory profile
Weightless slip; sets quickly. No added fragrance. Built for measured, elegant layers.
How to use
Morning
Apply to face and neck after UV-R. Allow ~60 seconds; follow with Serum Bioluminelle, then sunscreen.
Evening (optional)
If not using Advancement II, apply The Advancement before UV-R Concentrate. Keep layers measured for a satin, non-greasy finish.
Do
- Use daily for steady, cumulative results (peptides require consistency).
- Give layers ~60s to settle before the next step.
- Right-size the amount by climate and season.
Don’t
- Combine with harsh skincare that compromises the barrier.
- Rush OUMERE steps—concentrated formulas perform best in measured layers.
- Skip patch testing when introducing any product.
Full INCI
Wasabi Extract, Resveratrol, Watermelon Extract, Aloe Vera Concentrate, Beta-Glucan, Hydrolyzed Rice Bran Protein, Glycine Soja (Soybean) Protein, Oxidoreductases, Palmitoyl Tripeptide-5, Glycerin, Water (Aqua), Ursolic Acid, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Magnesium Chloride, Palmitoyl Dipeptide-5 Diaminobutyloyl Hydroxythreonine, Palmitoyl Dipeptide-5 Diaminohydroxybutyrate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol.
Scientific Note: OUMERE formulations are developed for cosmetic use, focusing on the visible health and aesthetic quality of the skin. They are not pharmaceuticals and are not intended to diagnose, treat, or cure any medical condition. The information provided is cosmetic and educational in nature.
Use in the evenings after cleansing, and before applying Serum Bioluminelle.
Shake bottle and apply a dime-sized amount and press into the skin.
Can be used in the mornings before applying Serum Bioluminelle in addition to the evening for more profound results.
Ingredients:
Wasabi extract, resveratrol, watermelon extract, aloe vera concentrate, beta glucan, Hydrolyzed rice bran proteins, glycine soya protein, oxidoreductases, palmitoyl tripeptide-5, glycerin, water, ursolic acid, Tetradecyl aminobutyroylvalylaminobutyric urea trifluoroacetate, magnesium chloride, palmitoyl dipeptide-5 diaminobutyloyl hydroxythreonine, palmitoyl dipeptide-5 diaminohydroxybutyrate, phenoxyethanol, sorbic acid, caprylyl glycol