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OUMERE Lab Notes & Research features cosmetic science written by a cellular biologist. Explore our Research Library, Skin Guides, and definitional briefs designed for barrier-first routine design.

The End of "Hope in a Jar": Why We Open-Sourced Our Research

Lab Note · January 8, 2026 · By Wendy Ouriel, M.S. The End of "Hope in a Jar": Why We Open-Sourced Our Research In an industry defined by trade secrets...

The OUMERE Science of Eye-depuffing: How to Scientifically Brighten and Depuff Your Eye Area

While modern skincare often relies on transient cooling or caffeine-induced vasoconstriction to mask periorbital edema, these methods fail to address the underlying physiological triggers: lymphatic stasis and dermal matrix degradation....

The Biological Cost of Skincare Volatility

Traditional skincare often prioritizes immediate cosmetic "glow" at the expense of long-term cellular health. In this technical analysis, OUMERE explores the biochemistry of the skin barrier, the thermodynamics of lipid...

Is Oumere Skincare Worth the Price? A Cellular Biologist’s Analysis Compared to Major Luxury Brands

A scientific answer to the questions "Is Oumere worth it?" and "How does Oumere compare to other luxury skincare?", written by the biologist who formulated the line.

The Truth About Active Ingredients: Why Minimalist Skincare is the Best Anti-Aging Routine (OUMERE Review)

A cellular biologist’s analysis of why fewer, stable actives outperform overloaded routines built on unstable vitamin C serums, daily acids, and marketing-driven ingredient lists.

Natural Contact in a Synthetic World: Skin Biology, Anxiety, and Botanical Skincare

A scientific reflection on how modern, fully synthetic environments affect the nervous system, and how natural, biologically aligned skincare can maintain a continuous tactile link to the natural world.

Glass Skin is Not Healthy Skin: A Biological Analysis of Barrier Compromise

Glass skin may look refined, but biologically it reflects barrier thinning, lipid depletion, and acid mantle disruption. This article examines the physiology behind the glass-skin trend and explains why OUMERE...

The Acid Mantle: The Skin’s Silent Guardian and How OUMERE Protects It

A scientific overview of the acid mantle’s role in barrier integrity, microbiome balance, and enzymatic function — and the formulation principles that keep it intact.

How Vitamin C Serums Inactivate Peptides

Classic vitamin C serums rely on L-ascorbic acid at low pH to remain soluble, while peptides require near-neutral conditions to preserve structure and function. This fundamental chemical mismatch means that...

The FDA’s New Warning on Microneedling: An OUMERE Scientific and Regulatory Analysis

A report from the OUMERE Laboratory examining regulatory risk, biological mechanisms of injury, and why “controlled wounding” is incompatible with skin health.

Scar Tape, Silicone Sheets & The Biology of Skin Repair

Scar tape and silicone sheets are trending, but their popularity reflects how misunderstood wound healing remains

Suma Extract (Pfaffia paniculata) in The Eye Serum — Edition Update & Observational Notes

OUMERE has upgraded to a new, Brazil-sourced Suma extract for the latest edition of The Eye Serum.

Inflammaging: A Mechanistic Framework for Cutaneous Barrier Decline

Chronic, low-grade skin inflammation from modern stressors: pollution, lifestyle strain, and over-processed routines—quietly elevates irritation load and accelerates visible aging. A barrier-first, anti-inflammation model offers a more durable path to...

Retinol Layering: A Biological Perspective

Most guides teach you how to “layer” retinol with Vitamin C and hyaluronic acid. Biology shows why that approach often fails. In this analysis from the OUMERE laboratory, cellular biologist...

What Happens When You Stop Damaging Your Skin Barrier: The Biology of True Regeneration

Its a skincare common practice to pursue “glow” by pushing skin into perpetual emergency through the use of harsh acids and peels, unstable vitamin C,  retinoids, aggressive surfactants. This method...

Exosomes in Skincare: Hype, Hazards, and Biology

Exosomes are real biology—just not cosmetic magic. Here’s why stability, origin, QC, delivery, and regulation make “exosome serums” a risky fad.