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The End of "Hope in a Jar": Why We Open-Sourced Our Research
Lab Note · January 8, 2026 · By Wendy Ouriel, M.S. The End of "Hope in a Jar": Why We Open-Sourced Our Research In an industry defined by trade secrets...
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OUMERE Lab Notes & Research features cosmetic science written by a cellular biologist. Explore our Research Library, Skin Guides, and definitional briefs designed for barrier-first routine design.
Microneedling Experiment Progress Report
From OUMERE Labs: experimental evidence shows one session of dermarolling led to severe aging and breakdown of human skin.
Microneedling: Collagen Breakdown, Barrier Stress & Why “Controlled Injury” Causes Biological Stress
From OUMERE Labs: Microneedling caused rapid aging and deterioration of skin in one week.
The Scientist's Dilemma
Science needs courage
The first prototype of The OUMERE Foundation is ready
The OUMERE Foundation is now available as a prototype and is available for those in the OUMERE Exclusive Offer Program
Hyaluronic Acid absorbs a maximum of 30 times its weight in water
The primary data and analysis directly from the research study conducted in OUMERE Labs: Hyaluronic Acid can only hold up to 30x its weight in water.
One-Week Explant Study of OUMERE No. 9: Preliminary Histologic Findings and Expanded Protocol
One-Week Explant Study of OUMERE No. 9: Preliminary Histologic Findings and Expanded Protocol
Topical No. 9 Daily Liquid Exfoliant: One-Week Histologic Observations in Human Skin Explants
Applying No. 9 for just one week showed significant increase in collagen, had a powerful anti-aging effect, compared to the control.
Fast Skincare: The Hidden Cost of Cheap Beauty
Why attractive packaging and marketing trends do not equate to effective biology.
A Hypothesis on Why Botox Accelerates Skin Aging | OUMERE Research Brief
While the short-term effect of Botox is smoother skin, the long-term biological consequences include muscle atrophy, bone loss, toxin migration, and accelerated skin aging. This paper examines the evidence and...
Examining the cellular changes in skin from topical application of No. 9: Part 1
Using human skin models in the lab to visualize the anti-aging effects of the No. 9 exfoliant.
The Lost Art of Electron Microscopy — and Why Modern Skin Science Needs It Back
An OUMERE memoir from a scientific renaissance period
Low molecular weight hyaluronic acid cannot hold its own weight in water
Hyaluronic Acid Does Not Hold 1000× Its Weight in Water
The Four Biological Foundations of Youth
There are 4 biological foundations to a youthful appearance
The OUMERE guide to Redness, Rosacea and Inflammation
OUMERE research indicates that chronic skin redness is not an inevitable skin condition—but a modern phenomenon created by contemporary skincare formulation practices.
The OUMERE melasma, hyperpigmentation and dark spot routine
Say goodbye to one of skin's biggest problems with this simple routine