The Advancement II™
A high-potency aqueous bio-fluid engineered for maximum signal transmission and visible structural density.
The Advancement II utilizes a rare 8-Peptide Complex suspended in an aqueous medium. By rejecting the occlusive waxes common in the industry, we ensure these expensive signaling molecules make direct contact with the skin's surface for unrivaled aesthetic results.

The Logic of Peptide Efficiency
Eliminating Entrapment
Standard peptide serums trap active molecules in heavy silicones and waxes. The Advancement II uses a water-light delivery system, allowing our Acetyl Octapeptide-3 complex to support the look of firmness without impedance.
Targeted DEJ Support
Specifically designed for evening repair, this serum targets the visible appearance of Dermal–Epidermal Junction (DEJ) fatigue. It supports the skin's structural bounce and a calmer, more even-looking tone associated with daily photo-exposure.
Systemic Superiority
The results achievable with The Advancement II are the product of the OUMERE system. By applying these signals after the dissolution of Step 1 and the brightening of Step 2, you initiate a level of structural refinement not possible with standalone products.
The Intelligence of Exclusion
NO FRAGRANCE
Aromatics serve no structural function. We exclude all fragrance to prevent neurogenic inflammation, ensuring signal transmission remains the absolute priority.
NO OCCLUSIVE WAXES
We reject the "industry standard" of heavy waxes that trap peptides. Our aqueous bio-delivery ensures your skin receives every signaling molecule directly.
NO SILICONES
Silicones create a plastic sheen that interferes with multi-layer absorption. OUMERE prioritizes biological access over temporary cosmetic "slip."
MOLECULAR INTEGRITY
Handcrafted in Palm Beach via small-cycle composition. We preserve the potency of our hydrolyzed Reishi and Resveratrol ferments for maximum efficacy.
Protocol & Ingredients
PM Ritual: Apply after Step 2: The Eye Serum. Allow 60 seconds to absorb; follow with Step 4: UV-R Concentrate.
Full INCI: Hydrolyzed Ganoderma lucidum (Mushroom) Extract, Water (Aqua), Glycerin, Wasabi Extract, Resveratrol, Tetrapeptide-21, Tetrapeptide-30, Hydrolyzed Rice Bran Protein, Glycine Soja (Soybean) Protein, Oxidoreductases, Palmitoyl Tripeptide-5, Ursolic Acid, Acetyl Octapeptide-3, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Magnesium Chloride, Palmitoyl Dipeptide-5 Diaminobutyloyl Hydroxythreonine, Acetyl Tetrapeptide-40, Caprylyl Glycol.
“Daily peptide discipline in a scientific system is the key to anti-aging.”
Proceed to PM Step 4: UV-R Concentrate →Scientific Note: OUMERE formulations are developed for cosmetic use only, focusing on the visible health and aesthetic quality of the skin. They are not pharmaceuticals and are not intended to diagnose, treat, or cure any medical condition.
Apply The Advancement in the morning and the Advancement Il in the evening. After cleansing with the Oil Dissolution Theory cleanser and applying the OUMERE Eye Serum, dispense several drops of the
Advancement Il to clean hands and press into skin. The Advancement II can be applied to the face, neck and décolleté. Wait one minute before proceeding to your next OUMERE step.
Hydrolyzed Ganoderma Lucidum (Mushroom) Extract, Water, Glycerin, Wasabi Extract, Resveratrol, Tetrapeptide-21, Tetrapeptide-30, Hydrolyzed Rice Bran Proteins, Glycine Soya Protein, Oxidoreductases, Palmitoyl Tripeptide-5, Ursolic Acid, Acetyl Octapeptide-3, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Magnesium Chloride, Palmitoyl Dipeptide-5 Diaminobutyloyl Hydroxythreonine, Acetyl Tetrapeptide-40, Caprylyl Glycol.
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