Limited to 100 units for this launch. Created individually — never mass produced.
Cellular Reprogramming Concentrate
Recalibrate the Appearance of Youth.
Advancement II Concentrate Serum is designed for those who demand more than cosmetic enhancement — a next-generation formulation inspired by the science of cellular reprogramming to support the visible renewal of aging skin.
With the highest concentration of bioactive peptides in the OUMERE range, Advancement II is crafted to target the visible signs associated with cellular senescence and to promote the skin’s natural renewal processes while you sleep.
This is not surface-level skincare.
It is a formulation designed to support the skin’s intrinsic resilience — helping to optimize the appearance of firmness, elasticity, and vitality over time.
Key Benefits:
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Cellular Renewal Support: Inspired by cellular reprogramming research to promote visible skin revitalization.
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Senescence-Targeted Care: Formulated to address the visible effects associated with cellular aging.
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Bioengineered Peptide Concentration: Supports the appearance of smoother, firmer skin by optimizing natural collagen pathways.
Visible transformation begins where true skin health originates — deep within the skin’s natural renewal systems.
Discover how the Advancement II completes your OUMERE Routine.
50mL, can be used up to two times daily.
Made by OUMERE in OUMERE Labs, Palm Beach


What Sets the Advancement II Concentrate Apart:
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Unmatched Bioactivity:
Formulated with the highest concentration of bioengineered peptides and advanced signaling molecules, Advancement II is designed to support skin renewal at a level unparalleled in cosmetic science.Laboratory-Crafted Precision:
Each bottle is meticulously handcrafted in OUMERE’s private laboratory. Produced in limited cycles, the serum undergoes a month-long formulation process to ensure maximum potency and stability — a standard of precision impossible in mass production.Elite Molecular Engineering:
Advancement II combines cutting-edge peptides — including Tetrapeptide-21, Acetyl Octapeptide-3, and Palmitoyl Dipeptide-5 — with advanced bio-extracts such as Hydrolyzed Ganoderma Lucidum and Resveratrol. This fusion is formulated to address the visible signs associated with skin aging and promote the skin’s natural resilience.Visible Biological Renewal:
Rather than masking imperfections, Advancement II is designed to support the skin’s natural self-repair processes — visibly improving skin texture, density, and the appearance of youthful vitality over time. - Read about how the Advancement II fits into your OUMERE routine here.
Why Peptides Matter
Peptides are the building blocks of your skin's natural structure. They:
- Stimulate collagen and elastin production to firm and smooth the skin.
- Improve skin texture by repairing damaged cells.
- Reduce inflammation and promote an even, glowing complexion.
Most serums contain only a fraction of the peptides found in Advancement II Concentrate—not enough to deliver significant results. OUMERE's serum is designed for those who demand real, visible transformation, making it the definitive choice for unparalleled anti-aging care.
Apply The Advancement in the morning and the Advancement Il in the evening. After cleansing with the Oil Dissolution Theory cleanser and applying the OUMERE Eye Serum, dispense several drops of the
Advancement Il to clean hands and press into skin. The Advancement II can be applied to the face, neck and décolleté. Wait one minute before proceeding to your next OUMERE step.
Hydrolyzed Ganoderma Lucidum (Mushroom) Extract, Water, Glycerin, Wasabi Extract, Resveratrol, Tetrapeptide-21, Tetrapeptide-30, Hydrolyzed Rice Bran Proteins, Glycine Soya Protein, Oxidoreductases, Palmitoyl Tripeptide-5, Ursolic Acid, Acetyl Octapeptide-3, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Magnesium Chloride, Palmitoyl Dipeptide-5 Diaminobutyloyl Hydroxythreonine, Acetyl Tetrapeptide-40, Caprylyl Glycol.
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